Elevated mitochondrial membrane potential of circulating monocyte–platelet aggregates in patients with coronary heart disease
S Vogel, D Rath, J Lu… - International …, 2015 - internationaljournalofcardiology.com
Platelets play a critical role in the pathophysiology of acute coronary syndrome (ACS)[1].
Activation of platelets and interaction with circulating leukocytes are enhanced in patients
with ACS [2], indicating that platelets trigger inflammation during a coronary event [3].
Formation of monocyte–platelet aggregates constitutes a critical step in linking thrombosis
with inflammation [4], and increased numbers of circulating aggregates have been found in
patients with stable coronary artery disease (CAD)[5], ACS [6], and various other diseases …
Activation of platelets and interaction with circulating leukocytes are enhanced in patients
with ACS [2], indicating that platelets trigger inflammation during a coronary event [3].
Formation of monocyte–platelet aggregates constitutes a critical step in linking thrombosis
with inflammation [4], and increased numbers of circulating aggregates have been found in
patients with stable coronary artery disease (CAD)[5], ACS [6], and various other diseases …
