Invariant NKT (iNKT) cells constitute a distinct lymphocyte subset, and upon activation, iNKT
cells modulate the function of a wide variety of other immune cells including anti-tumor
effector cells in both a direct and indirect manner. Decreased numbers and a reduced
function of iNKT cells have been observed in patients with various malignant diseases, thus
correlating with a poor clinical outcome. Therefore, therapeutic intervention strategies aimed
at the recovery of functional iNKT cells would be an appropriate rationale for the treatment of …